Publications

Journal Articles

  1. Saraav I, Pandey K, Sharma M, Singh S, Dutta P, Bhardwaj A, Sharma S. Predicting promiscuous antigenic T cell epitopes of Mycobacterium tuberculosis mymA operon proteins binding to MHC Class I and Class II molecules. Infection, Genetics and Evolution. 2016 Jul 5;44:182-189.
  2. Pandey K, Sharma M, Saarav I, Singh S, Dutta P, Bhardwaj A, Sharma S. Analysis of the DosR regulon genes to select cytotoxic T lymphocyte epitope specific vaccine candidates using a reverse vaccinology approach. International journal of mycobacteriology. 2016 Mar 31;5(1):34-43.
  3. Sharma A, Gupta P, Kumar R, Bhardwaj A*. dPABBs: A Novel in silico Approach for Predicting and Designing Anti-biofilm Peptides. Scientific reports. 2016;6.
  4. Abinaya ENarang PBhardwaj A*. FROG – Fingerprinting Genome Variation Ontology. PLoS One, 2015 Aug 5;10(8):e0134693.
  5. Rajput NK, Singh V and Bhardwaj A*. Resources, challenges and way forward in rare mitochondrial diseases research. F1000Research 2015, 4:70.
  6. Sharma ADutta PSharma MRajput NKDodiya BGeorrge JJKholia TOSDD ConsortiumBhardwaj A*. BioPhytMol: A Drug Discovery Community Resource on Anti-mycobacterial Phytomolecules and Plant Extracts. Journal of Cheminformatics 2014, 6(1).
  7. Bhardwaj A*. Investigating the Role of Site Specific Synonymous Variation in Disease Association Studies. Mitochondrion, 2014, May 16(83), 8.
  8. Vashisht R, Bhat AG, Kushwaha S, Bhardwaj A, OSDD Consortium, Brahmachari SK. Systems level mapping of metabolic complexity in Mycobacterium tuberculosis to identify high-value drug targets. J Transl Med. 2014, Oct 11; 12(1), 263.
  9. Santosh RS, Tuteja A, Basu S, Subramanium A, Sundharraman S, KUMARI A, M. Vaidhyanathan M, MohanA, Mahalakshmi R, Shankaranarayanan S, Chordia,  Diyva SG, Virmani A, Joshi K, Yadav SK, Charyulu LN, Savitha R, Ajithavalli C, Rajendran D, Raiththa K, Alam S, Gandhi S, Kamath D, Sowmya S, Wani TH, Ahmad SS, OSDD Consortium, Vijayalakshmi*, Bhardwaj A*, Subodh S*.Open access Mycobacterium tuberculosis clone repository: a community resource by OSDD members. Current Science, 2013, 105 (10), 25.
  10. Vashisht R, Bhardwaj A, OSDD Consortium, Brahmachari SK. Social networks to biological networks: systems biology of Mycobacterium tuberculosis. Mol. BioSyst. 2013, 9, 1584-1593.
  11. K S, Jalali S, Scaria V, Bhardwaj A*. MitoLSDB: A Comprehensive Resource to Study Genotype to Phenotype Correlations in Human Mitochondrial DNA Variations. PLoS One 2013, 8 (4), e60066.
  12. Raghava GPS, Bhardwaj A et al. Open source software and web services for designing therapeutic molecules. Current Topics in Medicinal Chemistry 2013, 13 (10), 1172-1191.
  13. Vashisht R, Mondal AK, Jain A, Shah A, Vishnoi P, Priyadarshini P, Bhattacharyya K, Rohira H, Bhat AG, Passi A, Mukherjee K, Choudhary KS, Kumar V, Arora A, Munusamy P, Subramanian A, Venkatachalam A, Gayathri S, Raj S, Chitra V, Verma K, Zaheer S, Balaganesh J, Gurusamy M, Razeeth M, Raja I, Thandapani M, Mevada V, Soni R, Rana S, Ramanna GM, Raghavan S, Subramanya SN, Kholia T, Patel R, Bhavnani V, Chiranjeevi L, Sengupta S, Singh PK, Atray N, Gandhi S, Avasthi TS, Nisthar S, Anurag M, Sharma P, Hasija Y, Dash D, Sharma A, Scaria V, Thomas Z; OSDD Consortium, Chandra N, Brahmachari SK, Bhardwaj A*. Crowd Sourcing a New Paradigm for Interactome Driven Drug Target Identification in Mycobacterium tuberculosis. PLoS One 2012; 7 (7), e39808.
  14. Anand P, Sankaran S, Mukherjee S, Yeturu K, Laskowski R, Bhardwaj A, Bhagavat R; OSDD Consortium, Brahmachari SK, Chandra N. Structural Annotation of Mycobacterium tuberculosis Proteome. PLoS One. 2011; 6(10): e27044.
  15. Bhardwaj A, Scaria V, Raghava GPS, Lynn AM, Chandra N, Banerjee S, Raghunandanan MV, Pandey V, Taneja B, Yadav J, Dash D, Bhattacharya J, Misra A, Kumar A, Ramachandran S, Thomas Z. Open Source Drug Discovery Consortium, Brahmachari SK, Open Source Drug Discovery- a new paradigm of collaborative research in Tuberculosis drug development. Tuberculosis, 2011 Sep; 91(5):479-86.
  16. Bhartiya D, Maini J, Sharma M, Joshi P, Laddha SV, Jalali S, Patowary A, Purkanti R, Lalwani M, Singh AR, Chauhan R, Singh N, Bhardwaj A, Scaria V, Sivasubbu S. FishMap Zv8 update–a genomic regulatory map of zebrafish. Zebrafish, 2010, 7(2), 179-80.
  17. Bhardwaj A, Bhartiya D, Kumar N, Open Source Drug Discovery Consortium, Scaria V. TBrowse: an Integrative Genomics Map of Mycobacterium tuberculosis. Tuberculosis, 2009, 89, 386–387.
  18. Bhardwaj A*, Mukerji M, Sharma S, Paul J, Gokhale CS, Srivastava AK, Tiwari S. MtSNPscore: A combined evidence approach for assessing cumulative impact of mitochondrial variations in disease. BMC Bioinformatics, 2009, 10 (Suppl 8), S7.
  19. Bhardwaj A. et al. Mycobacterium tuberculosis systems biology data in R, Biobytes, 2009, 5, 40-48.
  20. Indian Genome Variation Consortium. Genetic landscape of the people of India: a canvas for disease gene exploration. J. Genet. 2008, 87, 3–20.
  21. Bhardwaj A, Tiwari S. Evaluating the Association of Mitochondrial SNP Haplotypes with Disease Phenotypes using a Novel in silico Tool E-MIDAS. ICIT, 9th International Conference on Information Technology (ICIT’06), 2006, 17-20.

Science Translational Medicine Editor Choice Articles

  1. Bhardwaj A, Personalized cancer medicines. Sci. Transl. Med. 25 March 2015, 280ec48.
  2. Bhardwaj A, A molecular patch for DMD. Sci. Transl. Med. 11 February 2015, 7:274ec24.
  3. Bhardwaj A, Ctrl-Alt-Del: Host-Targeting Anti-Angiogenic Agents as Adjunct Therapy for Tuberculosis. Sci. Transl. Med. 24 December 2014 6:268ec218.
  4. Bhardwaj A, Cholesterol Therapy That’s Not Chopped Liver. Sci. Transl. Med. 12 November 2014 6:262ec193.
  5. Bhardwaj A, Synthetic Lethality: Drug Repurposing with a Difference. Sci. Transl. Med. 1 October 2014 6:256ec167.
  6. Bhardwaj A, Harnessing the Crowd for Neurology Research. Sci. Transl. Med.  20 August 2014 6:250ec141.
  7. Bhardwaj A, Dissecting the Enigma of Mycobacterium tuberculosis Pathogenesis. Sci. Transl. Med. 9 July 2014 6:244ec116.
  8. Bhardwaj A, Reactive Species Contribute to Antibiotic-Mediated Killing. Sci. Transl. Med.   28 May 2014 6:238ec92.
  9. Bhardwaj A, “Antigenomic” RNA as a Therapeutic Tool for Mitochondrial Diseases. Sci. Transl. Med. 16 April 2014 6:232ec66.

Book Chapters

  1. Singh V, Rajput NK, Gupta P, Bhardwaj A. Mitochondrial Genomics: Emerging Paradigms and Challenges. Elesvier – Medical and Health Genomics. June 2016.
  2. Bhardwaj A* et al. Software Platform for Metabolic Network Reconstruction of Mycobacterium tuberculosis. Springer – Systems Biology of Tuberculosis 2013, 21.
  3. Bhardwaj A*, Scaria V, Thomas Z, Adayikkoth S, Open Source Drug Discovery Consortium, Brahmachari SK. Book chapter entitled “Collaborative tools to accelerate neglected diseases research” in the book “Collaborative Computational Technologies for Biomedical Research”. Wiley and Sons. May 2011.

Popular Science Articles

  1. Sugumaran G, Dutta P, Ramachandran S, Wild D, Blundell T and Bhardwaj A*. Predictive Sciences for Drug Discovery. Science Reporter, 2014, 51, 32-36. NISCAIR-CSIR, ISSN 0036-8512.
  2. Bhardwaj A*, Scaria V, Patra D, Open Source Drug Discovery Consortium. Open source drug discovery: a global collaborative drug discovery model for tuberculosis. Science and culture, January-February, 2011, 77, 1–2, 22-26.

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