Prasun Dutta

IMG_20140609_115817

POSITION: Project Fellow (Currently PhD student in Developmental Biology Group at the Roslin Institute, The University of Edinburgh, UK)

PUBLICATIONS:
Dutta P, Sharma A, Sharma M, Rajput NK, Dodiya B, Georrge JJ, Kholia T; OSDD Consortium, Bhardwaj A. BioPhytMol: a drug discovery community resource on anti-mycobacterial phytomolecules and plant extracts. J Cheminform. 2014 Oct 11; 6(1):46. eCollection 2014. PMID: 25360160

Sushil Kumar Tomar, Prashant Kumar, Soneya Majumdar, Varun Bhaskar, Prasun Dutta, Balaji Prakash, Extended C-terminus and length of the linker connecting the G-domains are species-specific variations in the EngA family of GTPases, FEBS Open Bio, Volume 2, 2012, Pages 191-195, ISSN 2211-5463, DOI: 10.1016/j.fob.2012.07.009. PMID: 23650599

Sugumaran, G., P. Dutta, S. Ramachandran, D. Wild, T. L. Blundell and A. Bhardwaj (2014). Predictive Sciences for Drug Discovery. Science Reporter, NISCAIR-CSIR, India. 51: 32-36, ISSN 0036-8512

EDUCATIONAL QUALIFICATIONS:
M.Sc. Bioinformatics
Sep 2010 – Nov 2011
School of Biological Sciences, The University of Edinburgh, Scotland, UK (Upper Second Class)

B.Tech. Bioinformatics
July 2005 – Sep 2009
Dr. D. Y. Patil University, Pune, India (72%, First Class with Distinction, CGPA: 8.58/10.0)

AWARDS:
1) Royal Society of Chemistry (RSC)-OSDD Ambassador Award, 2014 (one of the seven awardees from India)

2) Best Poster Award at Indo-US conference in Molecular Modelling and informatics in drug design, 2014

3) International Travel Award from the Council of Scientific and Industrial Research (CSIR), 2014

4) International Travel Award from Centre for International Co-operation in Science (CICS), 2014

5) Recipient of the ‘Saltire Award’ for volunteering work, 2011

TECHNICAL SKILLS:
Structural Bioinformatics and Computational Drug Discovery: Protein-protein Docking (Hex, PatchDock), In-silico Protein-Protein interaction studies (Pisa, Coot, CCP4), Binding Site and Hot Spot Analysis (STP, SMAP), Homology Modeling and Validation (Modeller, Swiss Model, ProSA, RAMPAGE, PROCHECK), Energy minimization (YASARA, SPDBV), Molecular and Electrostatic visualization (Pymol, Chimera), Ab-initio Modeling (I-Tasser), Marvin Sketch, Virtual Screening (Autodock 4.0, Vina), Lead identification through High-Throughput Virtual Screening (LIDAEUS), In-silico Protein-Ligand interaction studies, Qualitative Analysis of protein active site, Galaxy workflow management system, chemical structure similarity, ChemAxon software suite
Bioinformatics: Sequence Analysis (BLAST, T-Coffee, ClustalX and W2, UCSC Genome Browser), Phylogenetic Analysis (MEGA), Secondary Structure Prediction (Jpred)
Bioinformatics Databases: PDB, PIR, NCBI, EMBL, SIB
Computing: Perl Scripting, Operating Systems such as Windows (XP, Vista, 7, 8.1) and Linux (Fedora, Ubuntu)
Wet Lab: Protein purification technique from bacterial system through metal affinity chromatography and other molecular biology techniques such as PCR, Expression checking, SDS PAGE, Hanging drop protein crystallization

TALKS, PRESENTATIONS AND POSTERS:
1) Poster on ‘Battling Tuberculosis through Open Source Resources in Drug Discovery’ at Joint EMBL-EBI-Wellcome Trust Workshop on Resources in Computational Drug Discovery, 2014 in EMBL-EBI, Hinxton, UK

2) Poster on ‘Multi-pronged Innovative Predictive Sciences Approaches to Drive Open Source Drug Discovery’ in the Indo-US conference in Molecular Modelling and informatics in drug design, 2014 in NIPER, Mohali, India

3) Talks on chemoinformatics resources in CSIR-OSDD unit, New Delhi, India; Jubilant Biosys, Bangalore, India; CSIR-Indian Institute of Chemical Technology, Hyderabad, India; Osmania University, Hyderabad, India; Department of Chemistry, University of Calcutta, Kolkata, India; Indian Institute of Chemical Biology, Kolkata; Indian Institute of Technology, Guwahati, India

4) Workshop coordinator and resource person for ‘Protein Modeling and Docking Studies for Rational Drug design: A Workshop for Science Students (12th-13th Mar 2014)’ organized by OSDD-unit and Miranda House (Delhi University)

5) Workshop coordinator and trainer for ‘Hands-on training in Protein Modelling and docking studies for rational drug design (23rd-24th Dec, 2013)’ organised by OSDD-unit, Jawaharlal Nehru University and Delhi University

6) Talk on Drug Discovery Technologies for ‘Certificate course in Bioinformatics and in-silico Drug Discovery’ at Acharya Narendra Dev College, University of Delhi, India, 2012

7) Scientific research paper presentation on Structural Biology in ‘Protein Structure Determination’ module at the University of Edinburgh, 2011

8) Scientific report writing proving the suitability of the chosen drug target in ‘Drug Discovery’ module at the University of Edinburgh, 2011

9) B.Tech. Thesis presentation in the final semester at Dr. D. Y. Patil University, 2009

10) Summer Research Project presentation in ‘Seminars in Bioinformatics’ module at Dr. D. Y. Patil University, 2008

11) Poster on ‘Pharmacogenomics’ addressing gene expression, drug effects, components and its benefits at the college technical fest ‘Prometheus-07’

12) Working model and poster of a ‘Bio-gas plant’ addressing the making, storage and effective uses of bio-gas at ‘Prometheus-07’

Contact me: prasundutta87@gmail.com/prasundutta87@yahoo.co.in

Detailed CV

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