This module of dPABBs allows the user to submit a peptide library with multiple sequences (in FASTA format) and predicts whether these are biofilm-active or inactive, employing the SVM/Weka-based model specified by the user. The desired physicochemical properties (such as hydrophobicity, charge, hydrophilicity etc.) can also be selected and are displayed accordingly. Further, all the possible mutants of these peptides can be generated via successive amino acid substitutions at each position, and the pre-selected model predicts their activity.

Paste Peptide Sequence(s) in FASTA format:

OR Upload peptide sequence file:

Select model: SVM based: Whole amino acid composition (Whole AAC)   Selected 14 residue composition (Sel_14_res)    NT5 residue-binary pattern profile (NT5 BPP)   WEKA based: Whole amino acid composition (Whole AAC)   Selected 8 residue composition (Sel_8_res)    NT5 residue-binary pattern profile (NT5 BPP)   SVM threshold: -1.0 -0.9 -0.8 -0.7 -0.6 -0.5 -0.4 -0.3 -0.2 -0.1 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0

Physicochemical property: Check / Uncheck All